NSP-DMAE-HEG-Glu-NHS is an activated acridinium ester labeling reagent containing a hexa(ethylene glycol) (HEG) spacer arm and a glutarate NHS ester. The long hydrophilic HEG linker reduces steric hindrance and non-specific binding, making it particularly suitable for labeling small molecules, haptens, and biomolecules in chemiluminescent immunoassays. It is a key component of Cyclosporine A tracers and is used in clinical diagnostics for therapeutic drug monitoring.
NSP-SA-NHS
Price range: $398.00 through $1,990.00
D-Luciferin potassium salt
$398.00
NSP-DMAE-HEG-Glu-NHS
$498.00
| Purity | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| 98% | 1mg | $498.00 | In stock |
Description
Additional information
| Size |
1mg |
|---|---|
| Purity |
98% |
| M.F. |
C47H58N4O16S |
| M.W. |
967.05 |
| Appearance |
Solid |
| Storage |
-20°C, sealed storage, away from moisture and light |
| Smiles |
O=C(OC=1C(=CC(=CC1C)C(=O)NCCOCCOCCOCCOCCOCCNC(=O)CCCC(=O)ON2C(=O)CCC2=O)C)C3=C4C=CC=CC4=[N+](C=5C=CC=CC53)CCCS(=O)(=O)[O-] |
Biological activity
| Biological target: | Acridinium ester with HEG spacer for chemiluminescent labeling and small molecule tracers |
| In vitro activity: | Emission wavelength: 430–480 nm (intense blue flash); Kinetics: flash-type, complete within 1–5 seconds; Light output: ~50% higher than NSP-DMAE-NHS (HEG-spacer acridinium esters); Key feature: third-generation acridinium ester with hexa(ethylene glycol) (HEG) hydrophilic spacer that reduces steric hindrance and non-specific binding; Signal purity: acridone dissociates from labeled biomolecule before emission, avoiding macromolecular interference; Conjugation: glutarate NHS ester couples to amine-containing biomolecules; Applications: small molecule/hapten labeling, Cyclosporine A tracers, therapeutic drug monitoring (TDM) |
| In vivo activity: |
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