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4'-Hydroxy-2,4-dimethoxychalcone
4'-Hydroxy-2,4-dimethoxychalcone $1,207.50

Neohesperidin dihydrochalcone

CAS Number: 20702-77-6
Synonym: Neohesperidin dc; Neohesperidin dhc; neohesperidine DC; hoxyphenyl)propan-1-one; Neohesperidin dihydrochalcone ,EP; Neohesperidin dihydrochalcone hydrate

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    SKU: ACU080971 Category:
    Description

    Neohesperidin dihydrochalcone belongs to the flavonoid class of polyphenolic natural products, featuring a characteristic 15-carbon skeleton with two benzene rings connected by a heterocyclic pyran ring, where the pattern of hydroxylation and glycosylation determines its specific biological properties. This compound occurs naturally in a wide variety of edible plants, including citrus fruits, berries, onions, tea leaves, and soy products, with dietary intake associated with reduced risk of chronic diseases through antioxidant and anti-inflammatory mechanisms The compound shows significant bioactivity as an antioxidant, anti-inflammatory agent, and enzyme inhibitor, with additional reported antimicrobial, antiviral, and anticancer activities that make it a promising candidate for nutraceutical and pharmaceutical development As a flavonoid, this compound exhibits potent antioxidant activity by scavenging free radicals and chelating metal ions, along with anti-inflammatory, antimicrobial, and anticancer properties that contribute to its well-documented health-promoting effects Its antioxidant mechanism involves direct scavenging of reactive oxygen species, inhibition of pro-oxidant enzymes, and upregulation of endogenous antioxidant defense systems through Nrf2 pathway activation, with the phenolic hydroxyl groups serving as hydrogen atom donors to stabilize free radicals This compound finds application in functional foods, dietary supplements, and cosmetic formulations due to its antioxidant and anti-aging properties, while also being studied for therapeutic potential in metabolic syndrome, cancer prevention, and inflammatory bowel disease through targeted delivery systems

    Additional information
    M.F.

    C28H36O15
    M.W.

    612.58
    Appearance

    Powder
    Smiles

    C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C(C(=C3)O)C(=O)CCC4=CC(=C(C=C4)OC)O)O)CO)O)O)O)O)O
    Storage

    Store at room temperature for short-term use; store at -20°C for long-term storage.
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