Blumeatin is a flavonoid compound characterized by a C6-C3-C6 carbon skeleton consisting of two aromatic rings linked by a three-carbon bridge that typically forms a heterocyclic pyran ring, with hydroxyl groups contributing to its antioxidant capacity. Flavonoids of this type are ubiquitously distributed in the plant kingdom, found in fruits, vegetables, seeds, flowers, and bark of numerous plant species, where they function as UV protectants, pigment molecules, and defense compounds against microbial pathogens As a flavonoid, this compound exhibits potent antioxidant activity by scavenging free radicals and chelating metal ions, along with anti-inflammatory, antimicrobial, and anticancer properties that contribute to its well-documented health-promoting effects The compound shows significant bioactivity as an antioxidant, anti-inflammatory agent, and enzyme inhibitor, with additional reported antimicrobial, antiviral, and anticancer activities that make it a promising candidate for nutraceutical and pharmaceutical development Its antioxidant mechanism involves direct scavenging of reactive oxygen species, inhibition of pro-oxidant enzymes, and upregulation of endogenous antioxidant defense systems through Nrf2 pathway activation, with the phenolic hydroxyl groups serving as hydrogen atom donors to stabilize free radicals This compound finds application in functional foods, dietary supplements, and cosmetic formulations due to its antioxidant and anti-aging properties, while also being studied for therapeutic potential in metabolic syndrome, cancer prevention, and inflammatory bowel disease through targeted delivery systems
Blumeatin
CAS Number: 118024-26-3
Synonym: 5,3′,5′-trihydroxymethoxylflavanone; 5,3′,5′-Trihydroxy-7-methoxyflavanone; 5,3′,5′-Trihydroxy-7-methoxy-2,3-dihydro-flavone; (S)-2-(3,5-Dihydroxyphenyl)-5-hydroxy-7-methoxychroman-4-one; (2S)-2-(3,5-dihydroxyphenyl)-5-hydroxy-7-methoxy-chroman-4-one; (2S)-2-(3,5-Dihydroxyphenyl)-5-hydroxy-7-methoxy-2,3-dihydrochromen-4-one
| M.F. |
C16H14O6 |
|---|---|
| M.W. |
302.28 |
| Appearance |
Powder |
| Smiles |
COC1=CC(=C2C(=O)C[C@H](OC2=C1)C3=CC(=CC(=C3)O)O)O |
| Storage |
Store at room temperature for short-term use; store at -20°C for long-term storage. |
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